Microinvasion is reported in up to nine per cent of mucinous borderline tumours of intestinal-type.1 Invasive foci may consist of single cells, small clusters, glands
In one report, 44 "mucinous borderline tumor with microinvasion" is used for those tumors lacking intraepithelial carcinoma, and "mucinous borderline tumor with microinvasive carcinoma" is used for those containing intraepithelial carcinoma. As noted earlier for the analogous serous tumors,
invasion of < 5 mm in greatest dimension is defined as microinvasion, regardless of number of foci; tumors with microinvasion are considered SMBT (“SMBT with microinvasion”). 2018-08-01 Two of 13 (15%, 95% CI 8.7, 21.3) patients with microinvasion died of recurrent invasive cancer, whereas only 1 out of 113 patients without microinvasion died of recurrent borderline tumor (OR 20.4, 95% CI 1.2, 239). All 3 patients with an aggressive disease course and poor outcome had increasing CA 125 levels at the time of recurrence. Comments: Borderline clear cell adenofibroma with a 2mm focus of microinvasion in a 10 cm tumor. The remainder of the tumor was composed entirely of benign areas.
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Borderline tumors occur in a variety of histologies, as in epithelial ovarian carcinoma . The majority of cases are serous or mucinous. Rarely, endometrioid, clear-cell, or transitional cell (Brenner) borderline tumors are found. Serous borderline tumors of the ovary: a long-term follow-up study of 137 cases, including 18 with a micropapillary pattern and 20 with microinvasion.
1 Although they generally occur in older women (mean ages 51–54 years), mucinous borderline tumors and carcinomas are more common in the first two decades than their serous counterparts.
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The chance of recurrence is minimal. I would ask the doctor to explain exactly what is meant by microinvasion, what type of follow up he suggests, if he has had experience with other borderline patients and how they have progressed. Endocervical-like mucinous borderline ovarian tumors (E-LMBOTs) or APE-LMOTs with microinvasion are defined as tumors with one or more foci of single cells, irregular glands, or small nests of confluent mucinous cells infiltrating the underlying stroma.
2012-09-01
There were no micropapillary areas in any of the carcinomas, although cribriform pattern was seen in these tumors. Conclusions: Advanced stage at diagnosis was the most important prognostic marker in patients with SBT. Micropapillary tumor is a growth pattern of serous borderline tumor which shows proliferation of the tumor cells in elongated, thin micropapillae with little or no stromal support emerging directly from a lining of a cyst or from large papillae in a non-hierarchical pattern.
2 Standard therapy for Stage I serous borderline tumors is comprised of surgery alone. However, for women with serous borderline tumors with peritoneal
Borderline tumour (Required or recommended) Reason/Evidentiary Support Histologic Type (Required) Terminology for ovarian borderline tumours has evolved over several years.1,2 The preferred terminology is borderline tumour, for example serous or mucinous borderline …
As indicated above, survival of patients who had tumors that showed microinvasion is 100%, and survival of patients with lymph node involvement is 98%.
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The diagnosis of IECA was based on the presence of marked nuclear atypia (grade 3).
27 non-invasive peritoneal implants (epithelial or desmoplas- tic). These pathologic features all
A borderline tumor, sometimes called low malignant potential (LMP) tumor, is a distinct but yet heterogeneous group of tumors defined by their histopathology as
is important in difficult cases, particularly in borderline tumors of the ovary. The upper size limitfor microinvasion has been arbitrarily set at 10 mm2 (10). 1 Mar 2012 In 12 series of serous borderline ovarian tumours with microinvasion (n=133), 20 patients had recurrence (15%), including 35% (seven of 20)
29 Dec 2017 Keywords: borderline ovarian tumor; BOT; recurrence; survival; treatment Stromal microinvasion was defined as the presence of stromal
31 May 2000 Ovarian tumors of low malignant potential (LMP) would benefit from a new name The name “borderline ovarian tumors” suggests that these tumors and “ microinvasion” as predictors of progression; the M. D. Anderson and
14 Oct 2017 9.1 Serous borderline tumor, micropapillary pattern.
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Ovarian mucinous borderline tumours of intestinal type – a pathologist’s perspective. ‘Mucinous tumors of ovary are among the most difficult ovarian neoplasms for surgical pathologists to interpret.’ Hart WR.1 Mucinous tumours of the ovary comprise an estimated 10–15 per cent of all primary ovarian epithelial tumours. These tumours are characterised by mucinous differentiation of the
• Lymph node 5 May 2015 Key Words: Borderline ovarian tumor, fertility preservation, ovarian conservation carcinoma, and microinvasion; implant type (invasive vs. Microinvasion was observed in 5.3% and a micropapillary pattern in 12.6%. Borderline tumors of the ovary (BOTs) represent a specific group of epithelial Invasion less than these measurements is classified as “micro-invasion” with a borderline mucinous tumor. MOC is typically the intestinal type, but the Microinvasion is reported in up to nine per cent of mucinous borderline tumours of intestinal-type.1 Invasive foci may consist of single cells, small clusters, glands Borderline ovarian tumours are abnormal cells that form in the tissue covering the ovary.